8 Mechanism of action specific Inhibit voltage gated Ca2+ channel bind at inner side of the membrane and bind more selective to channel in depolarized cell.The result is marked decrease Ca2+current …………. SM relaxation.
19 Toxicitiescommon toxicitiesfacial FlushingDizzinessNauseaPeripheral edemagingival hyperplasiaConstipation (verapamil)Reflex tachycardia (esp. for DHP but not for verapamil, diltiazem)High dose; cardiac depression, cardiac arrest, bradycardia, AV block
Your consent to our cookies if you continue to use this website.