33 Characteristics of Antiseptic Agents Agent Bact killing Antimicrobial activity Residual time gm gm fungi activityAlcohol fast E E G NoneCHG Intermediate E G EIodophor Intermediate E G G MinimalAlc/iodine fast E E G varies withcombination formulationsAlc/CHG fast E G G excellent withcombination repeated useE = excellent G = good CHG=chlorhexidine gluconateHICPAC Guideline for Prevention off SSI. AJIC 1999;27:97-132
34 Shelf-life of the antiseptics in Siriraj hospital package of antiseptics from pharmacy- 70%Alcohol- 2%chlorhexidine in Alcohol- 10%povidone iodine- Alcohol Hand Rub1 month- 0.5% hypochlorite- 7 Days after mixing- 24 hour after using- 2.4% glutaraldehyde14 days after mixing or the manufacturer’s recommendation
35 Appropriate use of antiseptics In Siriraj hospitalproceduresantiseptics- Venepuncture( blood test / IV line )70%AlcoholInjectionHemoculture- 2%chlorhexidine in Alcohol10%povidone iodine (for neonate )Body Cavity Puncture
36 procedures antiseptics - 2%chlorhexidine in Alcohol10%povidone Iodine (for neonate )Central line insertion10%povidone Iodine (for neonate )Hygienic Hand HygienAlcohol Hand Rub4% chlorhexidineSurgical Hand Wash7.5% iodophorUrinary catheter insertionNSS or sterile water- Arterial Puncture
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