What Has Happened Case of unusual pneumonia and Influenza like illness have occurred rapidly in Mexico since mid March, 2009. Few cases of Swine Flu reported in Southern California More Death were reported in Mexico, unusual high fatality Young people and people of working class were victim. It should be the end of seasonal Flu
What do we know, (and don’t) เจอ ไวรัสไข้หวัดใหญ่สายพันธ์ใหม่ New (novel) virus has been identified, a new virus contain genetic material of both human flu virus and swine flu virus. “We know it is a novel (new) virus, completely new - not regularly found” “We know it has happened (a new virus), but we do not know how it happened.” - (how the virus genetic material combined to make a new strain). Perhaps, the Mother Nature may know!
What do we know, (and don’t) จำนวนผู้ป่วย เพิ่มขึ้น เป็น 100, 1000, 1500,2000+ ใน Mexico ภายในระยะเวลา เพียง 5-6 weeks. จำนวนผู้เสียชีวิตพุ่งสูงขึ้นรวดเร็วใน ระยะแรก – case fatality rate 7 - 10% Several clusters, multi – area, and across society Human-to-Human transmission pattern No related pigs sick!, it is all human.
What do we know, (and don’t) Wave of human-to-human transmission in Mexico Imported cases in 21countries, air travel ( เกือบทั้งหมด ) Subsequence 2 nd outbreak, contact – US, Canada, Spain, Germany, S. Korea CNN – Sweden reported confirmed case travel from the US.
What we don’t know yet Uncertainty about – viral behavior, characterization, infectivity? Virulence, true Case Fatality ( ประมาณ 2-6%) Host range – Human, Swine, Poultry and other animals Need to know more and quickly -Biology – Interaction, Immunity, pathology Epidemiology pattern, speed, Clinical picture (?) – แบบสมบูรณ์ หรือรู้ชัดเจน พอ ?????? ? Second Wave ( -imminent)
Influenza A (H1N1): Morbidity & Mortality Up to 5 May 2009 1.Affected countries (21 countries) 3.Total dead (30 Cases) 4.CFR (2.01%) 2.Total confirmed (1490 Cases) ประเทศ casedeath 1.United States 4031 2.Mexico 82229 3.Canada 1400 4.Spain 570 5.United Kingdom 270 6.Israel 40 7.New Zealand 60 8.Austria 10 9.Germany 90 10.Netherlands 10 11.Switzerland 10 12.Denmark 10 13.China 10 14.France 40 15.Korea, Republic of 20 16.Costa Rica 10 17.Ireland 10 18.Italy 50 19.Colombia 10 20.El Salvador 20 21.Portugal 10
Imported case/Last caseLimited Indigenous/Last case Wide spread Indigenous/Last case Austria/ Apr 29New Zealand/ May 4United Kingdom/ Add Switzerland/ Apr 30Israel/ May 4United States/ Add NY TX CA AZ FL AL CO DE IL Netherlands/ Apr 30Korea, Republic of/ AddCanada/ Add BC AB ON NS NB China, Hong Kong SAR/ May 1 ? France/ May 4Spain/ Add Denmark/ May 1? Italy/ AddMexico Add Costa Rica/ May 2Germany/ Add - Bavaria Ireland/ May 3 Colombia/ May 4 El Salvador/ May 4 Portugal / May 4
SEOUL, May 5 (Xinhua)-- South Korean Health Ministry on Tuesday confirmed a 44-year-old woman as the country's second patient affected by the Influenza A/H1N1.
German gives nurse virus Berlin: Germany confirmed yesterday the second case of swine flu contract in Europe by someone who had not traveled to Mexico, in a nurse who treated the patient with virus. Bangkok Post – May 2 nd, 2009 Question ?? – Hospital Infection, Infectivity of new virus.